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No one knows what exactly causes fibromyalgia. Some possible triggers can include:

Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you should err on the side of caution and allow FDA do its job and demand some investigation be done so that the public is aware of the side effects and dangers of the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say anything to keep people on their medications.

Researchers discovered that participants using this drug to get a year, dropped a few pounds within one month and have kept the extra weight off through the entire 56 weeks of the study. Contrave can be a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more potent and safer.

Combo-pilling may be the newest fad or better yet the newest to come under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular could be the fact that since right now there aren't long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug can also raise blood pressure level and heartrate, and must not be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must not used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

"There were no indications of depression or suicidal thoughts in trial participants," said Fujioka.